Bi-est & Progesterone Duo Bundle 60-90 Day Supply
Estrogen + Progesterone Duo – Complete Hormone Balance Bundle (Save 10%)When estrogen and progesterone are out of sync, symptoms show up everywhere — poor sleep, mood swings, brain fog, weight gain, and more. This bundle combines two essential bio-identical hormones designed to bring them back into balance and help you feel like yourself again.A 60–90 day supply of both creams, bundled together at 10% savings.What's IncludedBi-Est Estrogen Cream (Estriol + Estradiol)Supports mood, brain clarity, skin health, and temperature regulation. Formulated with micronized Estriol USP and Estradiol USP in a nourishing base of aloe vera, coconut oil, shea butter, and olive oil.How to Use: Apply 1–4 pumps daily to clean, dry skin (inner arms, thighs, or abdomen). Rotate application sites for best absorption.Progesterone 75 mg CreamSupports restful sleep, calmness, and emotional balance. Formulated with micronized Progesterone USP plus Vitamin E, Retinol, and a nourishing botanical base.How to Use: Apply 1–4 pumps daily to clean, dry skin (inner arms, thighs, or abdomen). Rotate application sites for consistent delivery.Why This Duo Works Supports both estrogen and progesterone balance simultaneously Helps improve sleep, mood, and overall hormonal stability Designed for consistent transdermal absorption Addresses the root cause — not just the symptoms Save 10% vs. purchasing each cream separately Who It's For Women in perimenopause or menopause experiencing hormonal imbalance Those struggling with poor sleep, mood changes, or hot flashes Anyone looking for a natural, bio-identical hormone support approach These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Two hormones. One coordinated wellness story.
Estrogen and progesterone are the great collaborators of a woman’s life. They rise, fall and partner with each other through cycles, seasons and decades. As perimenopause and menopause quietly reshape the conversation between them, many women notice that supporting both hormones — not just one — is what makes a hormone-conscious routine truly feel personalized.
The Bi-est & Progesterone Duo Bundle pairs our Bi-Est Hormone Cream with our Bioidentical Progesterone Cream in a curated 60–90 day supply — a physician-guided approach to personalized hormone wellness that supports the way these two hormones are designed to work together.
- Bi-Est Hormone CreamBioidentical estriol + estradiol support
- Bioidentical Progesterone CreamThe calming, balancing counterpart
- 60–90 Day SupplyA meaningful runway for consistency
- Physician-GuidedUsed as part of a personalized plan
A partnership your body has been writing your whole life.
Estrogen and progesterone influence far more than reproduction. They’re threaded through mood, sleep, skin, cognition and the felt experience of everyday wellness. Learning how each one supports you is the first step toward a truly personalized routine.
The wellness hormone women miss when it shifts.
Bi-Est is a physician-favored blend of two bioidentical estrogens — estriol (E3) and estradiol (E2) — designed to support the many day-to-day roles estrogen plays for women through midlife and beyond.
- Skin HydrationEstrogen influences moisture retention, elasticity and the everyday softness we associate with healthy-looking skin.
- Temperature ComfortEstrogen plays a role in the body's natural temperature regulation — a familiar experience for many women in midlife.
- Mood & Emotional WellnessEstrogen interacts with mood-regulating pathways that support day-to-day emotional steadiness.
- Cognitive WellnessEstrogen is active in the brain, supporting focus, verbal fluency and the mental clarity women often notice shifting during transitions.
- Vaginal Tissue WellnessEstrogen supports the comfort, moisture and resilience of intimate tissues.
- Healthy AgingAs estrogen naturally shifts, thoughtful bioidentical support becomes an important part of a hormone-conscious wellness routine.
The calming counterpart to estrogen.
Bioidentical progesterone is often described as the “calming hormone.” It supports restful sleep, emotional balance and the felt experience of being at home in your own body.
- RelaxationProgesterone is known for its naturally calming influence — the hormone many women miss most.
- Healthy SleepProgesterone supports deeper, more restorative rest, especially during hormonal transitions.
- Emotional WellnessBalanced progesterone supports steady mood and a general sense of equilibrium.
- Hormonal BalanceProgesterone complements estrogen — the two are designed to work together, not compete.
- Estrogen Balance SupportProgesterone helps balance the effects of estrogen as part of a physician-guided wellness plan.
- Everyday ComfortThe felt experience of balanced progesterone often shows up as calm, patience and better sleep.
Educational content only. These statements have not been evaluated by the FDA and are not intended to diagnose, treat, cure or prevent any disease.
“Hormone wellness isn’t about a single hormone — it’s about the conversation between them.”
Balance is a duet, not a solo.
Estrogen and progesterone are designed to work in concert — supporting each other and creating the rhythm your body recognizes as balance. Many personalized hormone wellness programs include both, because supporting only one hormone can leave the story incomplete.
Complementary Support
Each cream plays a different role — together they support a fuller picture of hormone wellness.
Personalized Balance
Doses and ratios are tailored to your unique story, labs and lived experience.
Daily Consistency
A predictable morning and evening rhythm is how hormone wellness becomes a habit.
Physician-Guided Dosing
Used as part of a personalized plan built by Dr. Tammy and the Hormone Bliss team.
Wellness, Not Diagnosis
A supportive daily ritual for the transitions women navigate — not a disease treatment.
Whole-Woman Focus
Skin, sleep, mood, cognition and energy all live in the same body — we care for the whole story.
The everyday clues women often notice first.
Hormonal transitions rarely announce themselves. They tend to arrive quietly — in a night’s sleep that feels lighter, a familiar reaction that feels newer, or a mirror that suddenly reflects a different kind of tired.
If any of these feel familiar, personalized hormone testing and a conversation with a knowledgeable provider are the most reliable next steps. Start with our free hormone quiz or a Hormone Saliva Test.
- Hot flashes
- Night sweats
- Brain fog
- Mood changes
- Low energy
- Sleep disruption
- Vaginal dryness
- Skin changes
- Changes in libido
- New anxiety or restlessness
- Cycle irregularity
- Loss of everyday resilience
This list is educational and is not intended to diagnose any condition. Always consult a qualified provider for personalized guidance.
One thoughtful bundle. One coordinated ritual.
Coordinated Support
Both hormones together in one thoughtfully curated bundle — the way estrogen and progesterone are meant to be experienced.
Simplified Routine
One bundle. One order. One consistent daily rhythm — designed to fit inside your real life.
Better Overall Value
A curated 60–90 day supply makes long-term consistency easier and more approachable.
Physician-Guided Dosing
Used as part of a personalized plan built around your unique hormone story.
Designed To Be Used Together
Estrogen and progesterone are complementary — this bundle reflects how they're most often used.
Consistent Daily Ritual
A predictable morning and evening routine is what turns hormone wellness into a habit.
A morning and evening rhythm you’ll actually look forward to.
- 1Apply Bi-Est CreamSmooth onto clean skin as directed in your personalized plan.
- 2Begin The DayA grounding morning ritual — light, breath and a quiet moment for you.
- 3Stay HydratedStart with water before caffeine — your hormones will thank you.
- 4Prioritize MovementA walk, a stretch, a class — movement supports mood and metabolism.
- 1Apply Progesterone CreamThe calming close to your daily hormone ritual.
- 2Wind DownLower the lights, slow the pace, prepare for rest.
- 3Prioritize Restful SleepSeven to nine hours is where hormones do their most active work.
- 4Maintain ConsistencySame time, same place, most nights — that’s where results live.
Always follow the personalized dosing and application instructions provided by your Hormone Bliss provider.
Physician-formulated. Education-first. Built for real women.
Physician-Formulated
Every formulation is built from clinical experience with real women — not marketing trends.
Bioidentical Hormone Expertise
Deep experience with bio-identical hormones, translated into products women can trust.
Pharmaceutical-Quality Ingredients
Clean, thoughtfully chosen actives and carriers — the same standard behind every Hormone Bliss product.
Education-First Approach
We’d rather you understand your hormones than depend on us. Everything we publish is written to teach.
Personalized Hormone Wellness
Bundles are one part of a broader, individualized plan — never a one-size-fits-all shortcut.
Ongoing Hormone Coaching
From your first quiz to your fifth protocol adjustment, we stay with you for the long journey.
The bundle is one part of a bigger wellness story.
The women who feel best tend to pair their hormone routine with the small daily habits that quietly compound. Think of these as the foundation your Bi-Est & Progesterone Duo Bundle rests on.
Whole foods, colorful vegetables and healthy fats support the hormonal systems your bundle supports.
Seven to nine restorative hours is one of the highest-impact hormone habits you can build.
Chronic stress reshapes hormone patterns — breathwork and boundaries count as hormone care.
Consistent movement supports metabolism, mood and long-term hormonal wellness.
Well-hydrated tissues respond better to every part of your daily routine.
Muscle is metabolic. A few sessions each week supports bone density and healthy aging.
Small, repeatable habits compound over months and years — that’s where the results live.
The best plan is the one built around you — your labs, your symptoms, your life.
Questions? We’ve got answers.
A curated collection of the most common questions about bioidentical hormones, estrogen and progesterone.
See All FAQsExplore the rest of the Hormone Bliss collection.
Remove the guesswork with personalized at-home hormone testing.
The 'mother hormone' supporting your body's own downstream hormone story.
Bi-est, progesterone and DHEA thoughtfully combined in a single daily cream.
Support for healthy estrogen metabolism as part of your daily wellness plan.
Ongoing hormone coaching, member pricing and long-term support.
Deep-dive articles on hormones, healthy aging and personalized wellness.
Understand your hormones. Feel your best.
Estrogen and progesterone are a partnership worth understanding. Explore how a personalized, physician-guided approach to bioidentical hormone wellness can support the woman you’re becoming.